CD44 anticorps

N° du produit ABIN1177309

Cet anticorps Souris Monoclonal détecte spécifiquement CD44 dans FACS. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour CD44 anticorps (ABIN1177309)

Antigène: CD44

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 515

Détail du produit anti-CD44 anticorps

Marque: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Références pour anticorps anti-CD44 (ABIN1177309)

Kansas, Muirhead, Dailey: "Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans." dans: Blood, Vol. 76, Issue 12, pp. 2483-92, (1991) (PubMed).

Détails sur CD44

Antigène: CD44

Autre désignation: CD44 (Pgp-1, H-CAM, Ly24)

Sujet: Reacts with CD44, and 85 kDa glycoprotein that is expressed on leukocytes, erythrocytes, epithelial cells and weakly on platelets. CD44 is a member of the hyaladherin family of hyaluronan-binding proteins, with structural similarities to selectins. It has a functional role in cell migration, lymphocyte homing and adhesion during hematopoiesis and lymphocyte activation. 515 monoclonal antibody has been reported to be able to block cell adhesion to the hyaluronic acid. Flow cytometric analysis for CD44. Human peripheral blood lymphocytes were stained either with the Purified NA/LE Mouse Anti-Human CD44 antibody (solid line) or a Mouse IgG1 isotype control (dashed line) followed by a FITC Goat Anti-Mouse IgG/IgM polyclonal secondary antibody and analyzed on a BD FACScan™ instrument.
Synonyms: Pgp-1, H-CAM, Ly24

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling